Fat cells step in to help liver during fasting
This can be a UT Southwestern examine decided that the metabolite uridine helps the physique regulate glucose. This graphic depicts how the physique's fats cell-liver-uridine axis works to keep up vitality stability. Credit score: UT Southwestern How do mammals preserve two biologically essential metabolites in stability throughout instances when they're feeding, sleeping, and fasting? The reply might require rewriting some textbooks. In a examine revealed in Science , UT Southwestern Medical Middle researchers report that fats cells "have the liver's again," so to talk, to keep up tight regulation of glucose (blood sugar) and uridine, a metabolite the physique makes use of in a variety of basic processes corresponding to constructing RNA molecules, correctly making proteins, and storing glucose as vitality reserves. Their examine might have implications for a number of illnesses, together with diabe...